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Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must not be used in patients with uncontrolled high hypertension, in addition to by you are not heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients with a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients for the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking. From a psychiatric perspective, evidence implies that the ordinary neural mechanism for goal-directed behavior has been hijacked through the addiction, and malfunctions in a way that its ordinary functions are exaggerated and fixated on its object. An object creates a stimulus along with the person engages in a "goal-directed behavioral response" that generates a "natural high"(Bostwick & Bucci, 2008).
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