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The drug could also raise blood pressure levels and heartrate, and mustn't be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure levels and heartbeat and must not be used in patients with uncontrolled high blood pressure level, in addition to by a person with heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients for the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking. New UCLA study on smokers with mental, drug, and alcohol problems

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